The answer to this question is broken up into two parts:
It is certainly possible to travel from north to south, and east to west, in Botswana with a sedan car as all the major centres of the country are linked by tarmac road - as are all the neighbouring countries. Maun, also known as the Gateway of the Okavango, is easily accessible by SUV. From Maun tarmac roads lead to Namibia and the Caprivi, Zimbabwe, Zambia and South Africa.
The second part of the answer concerns access to the northern parks of Botswana in a SUV. It is not possible to enter the parks in a SUV. A 4 x 4 is essential as the roads are very sandy and corrugated. However, from Maun it is easy to access any of the safari camps and lodges of northern Botswana by light aircraft.
Leaving your vehicle in Maun you can enjoy a pampered safari at any number of the camps before returning to Maun for the homeward journey. There are a number of places to park your vehicle in Maun during a fly-in visit to the lodges in the Delta.
The road infrastructure of southern Africa is of a very high standard and the region is certainly the best suited for a self drive safari. South Africa, Namibia, Zambia and Zimbabwe can all be combined with a Botswana safari to provide an unforgettable SUV safari experience.
Many of the regions spectacular highlights can be accessed in a SUV, including the Namib Desert and Etosha in Namibia, Victoria Falls in Zambia, and the Kruger Park in South Africa, and combined with a Botswana excursion will provide the greatest travel experience on earth.